2-Chloro-3-amino-4-picoline (CAPIC) is a strategic building block for the preparation of nevirapine. a widely-prescribed non-nucleosidic reverse transcriptase inhibitor for the treatment of HIV-infected patients. A continuous synthesis to the bromo derivative of a CAPIC intermediate. 2-bromo-4-methylnicotinonitrile. https://www.globalspecialtyfoods.com/product-category/presses/
Investigating the continuous synthesis of a nicotinonitrile precursor to nevirapine
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