Stable integration in the host genome renders murine leukemia virus (MLV)-derived vectors attractive tools for gene therapy. Adverse events in otherwise successful clinical trials caused by proto-oncogene activation due to vector integration hamper their application. MLV and MLV-based vectors integrate near strong enhancers. active promoters. https://darthomes.shop/product-category/bowls/
BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements
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