The acrosome reaction (AR) is an exocytotic process essential for mammalian fertilization. It involves diverse physiological changes (biochemical. biophysical. and morphological) that culminate in the release of the acrosomal content to the extracellular medium as well as a reorganization of the plasma membrane (PM) that allows sperm to interact and fuse with the egg. https://www.roneverhart.com/POISON-OPEN-UP-AND-SAY-AHH-T-SHIRT/